Wednesday, October 13, 2010

Protein Data Bank


The protein Data Bank contains information about experimentally-determined structures of proteins, nucleic acids, and complex assemblies. These are the molecules that are found in living things such as bacteria, yeast, fungi and even human. The data are obtained from  X-ray crystallography or NMR spectroscopy. X-Ray crystallography is a method of determining the arrangement of atom in a structure. The data typically sent by scientists all over the world are freely accessible by public. We can use this Protein Data Bank to help us to understand the genomic microbiology.

RasMol is a computer program written for molecular graphics visualization intended. RasMol can be used to depict and explore the macromolecules structure in the Protein Data Bank. By using RasMol, we can view the structure of the molecules using several types of display and colours. As an example, the protein below is being view by using cartoon display.



From the Protein Data Bank, we can get information about the compound of the protein and some additional explanation about the protein. We also can know the author of the structure and the date of the structure is released.  For the above picture, the author of the protein is Duman R.E and Lowe J.Y and it is being published on 30tth June 2010. The above picture shows lon ATP dependent protease. This structure play important role in controlling the protein quality. 



This is lon ATP view by using ball and stick display




To know more about... Please click the link
Protein Data Bank Here
RasMol Here






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